Manipulation with molecules

Manipulation of single molecules in biology.

The mechanical manipulation of single biological molecules is stimulating new and exciting research in many fields of study, including molecular motor mechanics, biopolymer properties, protein unfolding, receptor-ligand interactions, and more. Some recent highlights include the elucidation of the coupling ratios of myosin and kinesin, the demonstration of oscillatory forces in dynein arms, the ...

STM Manipulation of Nanoscale Biological Molecules

Scanning-tunneling-microscope (STM) is an instrument not only used to see individual atoms by imaging, but also used to touch and pick-up the atoms or to hear their vibrations by means of manipulation and spectroscopy [1]. In this perspective, the STM can be considered as the eyes, hands and ears of the scientists connecting our macroscopic world to the exciting atomic and nanoscopic world. Her...

Coherent Laser Manipulation of Ultracold Molecules

INTERACTION OF PROTEINS WITH SMALL MOLECULES

Manipulation of Costimulatory Molecules by Intracellular Pathogens: Veni, Vidi, Vici!!

Some of the most successful pathogens of human, such as Mycobacterium tuberculosis (Mtb), HIV, and Leishmania donovani not only establish chronic infections but also remain a grave global threat. These pathogens have developed innovative strategies to evade immune responses such as antigenic shift and drift, interference with antigen processing/presentation, subversion of phagocytosis, inductio...